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2003 Midwest monkeypox outbreak
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2003 Midwest monkeypox outbreak : ウィキペディア英語版
2003 Midwest monkeypox outbreak

The 2003 Midwest monkeypox outbreak marked the first time monkeypox infection has appeared in the United States, and the first time in the Western Hemisphere. Beginning in May, 2003 a total of 71 cases of human monkeypox were found in five Midwestern states including Wisconsin (39 cases), Indiana (16), Illinois (12), Kansas (1), Missouri (2) and Ohio (1). The cause of the outbreak was traced to Gambian rats imported into the United States by an exotic animal importer in Texas. The rats were shipped from Texas to an Illinois distributor who housed them with prairie dogs. No deaths were reported. No human-to-human transmission was found. All cases involved direct contact with infected prairie dogs. Electron microscopy and testing by polymerase chain reaction and immunohistochemistry were used to confirm the causative agent was human monkeypox.〔Centers for Disease Control (CDC), Morbidity and Mortality Weekly Report. Atlanta, Georgia. (MMWR) July 11, 2003. (52) 27; 642-646.〕
==Background==
In May, 2003, a three-year-old Wisconsin resident was bitten by a prairie dog purchased from a local pet store.〔Linda Spice, “13 Sick After Prairie Dog Contact; Milwaukee Pet Store Employee, Two OthersRemain Hospitalized,” Milwaukee Journal Sentinel, June 6, 2003.〕 The child was hospitalized after developing fever of unknown origin (103.0F), swollen eyes, and a red vesicular skin rash. The child's parents also developed a rash, but no other symptoms.〔Todd Richmond. Four Get Monkeypox Virus from Prairie Dogs." Associated Press. 6/11/2003.〕 Physicians immediately associated the symptoms with the animal bite and reported the case to the Milkwaukee Health Department. Testing of both the child and the prairie dog confirmed the monkeypox virus as the causative agent.
Between May 15, 2003 when the three year-old index patient was first diagnosed through June 20, the date of the last patient with a laboratory confirmed case of monkeypox, a total of 71 people ranging in age from 1 to 51.

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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